Uvavanyo lwe-Antigen ye-COVID-19: Into omawuyazi

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Kuvavanyo olunomngcipheko ophantsi we-COVID-19, uvavanyo olukhawulezayo lwe-antigen lubonelela ngendlela ekhawulezayo nelula yokuhlola i-SARS-CoV-2 ekhaya.Ziluncedo ngakumbi ukuba uyazi okanye ukrokrela ukuba uye wachanabeka kwi-coronavirus kodwa awukwazi ukufumana uvavanyo lobuchwephesha (okanye ulinde iziphumo).
Uvavanyo lwe-antigen olugunyazisiweyo lwe-FDA lwasekhaya lunokubona usulelo olusebenzayo lwe-COVID-19, kubandakanya abantu abangenazimpawu, malunga nemizuzu eli-15.Lilonke, olu mvavanyo alunabuntununtunu njengovavanyo lokuxilongwa kweemolekyuli olwenziwa kwiilabhoratri.Nangona kunjalo, iziphumo zovavanyo lwe-antigen yasekhaya zinokubonelela ngedatha eyongezelelweyo-ukuba ayikhululekanga ngokupheleleyo-ngesimo somntu se-COVID-19, ngakumbi ukuba uvavanya rhoqo.Kuxhomekeke kwimeko yakho, kusenokuba sengqiqweni ukuba nolu vavanyo lukhoyo.
Khumbula, iziphumo ezingalunganga azithethi ukuba umntu akanayo i-COVID-19, kwaye ezi mvavanyo azenzelwanga ukuba zisetyenziswe njengendlela yokuxilongwa kuphela.UGqr. Matthew McCarthy, unjingalwazi onxulumene nezamayeza e-Weill Cornell School of Medicine, wathi: “Uvavanyo lwe-antigen yindlela engabizi kakhulu nelula yokuchonga abantu abanokuthi bosulele.”Kubantu abangenayo imbali eyaziwayo yokuvezwa kwe-COVID-19, "ukuba uya kuMbulelo, apho kukho abantu abangama-20 kwaye bonke bagonyiwe, unokwenza uvavanyo lwe-antigen ngaphambi kokuba uhambe ukuze uqiniseke ukuba awuyizisanga intsholongwane. itheko,” utshilo, ecaphula into enokusetyenziswa.
Kusenokuba yinto efanelekileyo ukwenza uvavanyo lwe-antigen olukhawulezayo ngaphambi kokunxibelelana nabantu abanokuthi bachaphazeleke ngakumbi kwintsholongwane.UGqr. Claire Rock, ugqirha wezifo zezifo kwiYunivesithi yaseJohns Hopkins yeSikolo sezoNyango, uthe: "Kwanabantu abagonywe ngokupheleleyo banokufuna ukuthatha enye yezi mvavanyo zifanelekileyo zasekhaya ngaphambi kokuchitha ixesha kunye nomakhulu," oqhuba inkampani yokubonisana ne-COVID-19. .
Uvavanyo lwe-antigen ye-COVID-19 ekhaya lunokuba lula kwaye lukhawuleze.Akukho mfuneko yokulinda idinga (okanye u-odole ikiti ngeposi kunye neesampuli zenqanawa) uze ulinde iziphumo zovavanyo lokuxilonga imolekyuli.Ngokwenza uvavanyo lwe-antigen ekhaya, unokuthatha imizuzu eyi-15 ukusuka kwi-swab ukuya kwisiphumo.Olu vavanyo luhlala lulula ukwenza, kwaye unokufunda iziphumo ngesandla (njengokusebenzisa uvavanyo lokukhulelwa ekhaya) okanye ngedijithali (usebenzisa i-app).
Uvavanyo lwe-antigen ye-COVID-19 alunabuntununtunu njengoxilongo lwemolekyuli.Ngokungafaniyo novavanyo loxilongo lwemolekyuli ye-COVID-19, ebandakanya ukukhulisa i-nucleic acid yentsholongwane ukuya kwinqanaba ekulula ukulibona, uvavanyo lwe-antigen lunokubona umkhondo wentsholongwane engaphuhliswanga, ngoko akukho lula ukufumanisa imiqondiso emincinci.(Musa ukulubhidanisa uvavanyo lwe-antigen kunye novavanyo lwe-antibody. Uvavanyo lwe-antibody lwenzelwe ukukhangela izilwa-buhlungu ezisabela kwintsholongwane kwaye azisetyenziselwa iinjongo zokuxilonga.)
Nangona uvavanyo lwe-antigen yasekhaya alunabudenge, xa kufunyaniswa iimeko ze-COVID-19 ezisebenzayo, neendlela zokuxilonga iimolekyuli ezifana novavanyo oluqhelekileyo lwegolide lwePCR azisoloko zichanekile, kuba iziphumo zixhomekeke, phakathi kwezinye izinto, ixesha lovavanyo..Ukuba wosule kwangethuba emva kokuba uqhagamshelwe, iziphumo zovavanyo lwakho zinokuba zingenayo nokuba unayo intsholongwane.Emva kokuba ungasasuleli, usenokufumana iziphumo zovavanyo lwe-PCR.
Ugqirha wezifo zesifo seklinikhi uRock uthe xa kuthelekiswa nokuxilongwa kwemolekyuli ye-COVID-19, uvavanyo lwe-antigen “alukho buthathaka kangako ukuba sifuna ukwazi ukuba kukho naziphi na iintsholongwane ezincinci, kodwa ukuba siyazijonga, zinobuntununtunu kakhulu” bona ukuba kukho umlinganiselo othile wentsholongwane, simele sixhalabele ukuba ubani uya kosulela abanye.”

"Sihlala sincoma ukuvavanya iintsuku ezintathu ukuya kwezintlanu emva kokuba sesichengeni." - UGqr.UMateyu McCarthy, uWeill Cornell School of Medicine
Ukuchaneka kovavanyo lwe-antigen yasekhaya kuxhomekeke kwinxalenye kubuntununtunu bovavanyo (amandla engxelo yovavanyo ukufumanisa iipositives eziyinyani), ukuchaneka kovavanyo (amandla engxelo ukubona izinto ezingalunganga), kunye nokuthembeka kwesampulu ( ingaba i-swab iqulethe iisampulu ezaneleyo okanye i-swabs Isisombululo sihlanjululwe yenye i-pathogen), kungakhathaliseki ukuba imiyalelo yomenzi ilandelwe ngokupheleleyo, ixesha ukususela ekugqibeleni owaziwayo okanye okrokrelwayo uqhagamshelwano kunye / okanye ukuqala kweempawu, kunye nomthamo wentsholongwane egazini. ixesha lovavanyo.(Olu mvavanyo okwangoku lugunyaziswe kubantu abaneminyaka emi-2 ubudala, ngaphandle kokuba naziphi na iisampuli zabantwana zifunyenwe kwaye ziqwalaselwe ngabantu abadala.)
Kwiimvavanyo eziqwalaselwe ugunyaziso losetyenziso olungxamisekileyo, umenzi wovavanyo kufuneka angenise idatha yeklinikhi kwi-FDA ukubonisa ubuntununtunu kunye neenkcukacha zovavanyo.Olunye uphando oluzimeleyo lubonise ukuba ubuntununtunu kunye neenkcukacha zovavanyo oluthile lwe-antigen ziphantsi kakhulu, ngakumbi xa zisetyenziselwa abantu abangenazimpawu.(Okwangoku kukho uvavanyo lwe-SARS-CoV-2 lwemolekyuli olufumanekayo olufumanekayo olugunyaziswe yi-FDA kwaye lunokusetyenziselwa ukusetyenziswa ekhaya ngokungxamisekileyo, okuthetha ukuba awudingi kuthumela iisampulu kwilabhoratri ukuze zivavanywe: Lucira COVID -19 All-In-One Test Kit xa kuthelekiswa novavanyo oluthile lwe-antigen olugunyazisiweyo lwe-FDA, inovakalelo olungaphezulu kancinci (95.2%) kwaye inokubonelela ngeziphumo kwimizuzu engama-30. Nangona kunjalo, okwangoku ayifumaneki kwiwebhusayithi kaLucira kunye neAmazon. kanye.)
Ngexesha lokupapashwa, kwakunzima ukufumana iimvavanyo ze-antigen zasekhaya kuba utyando lwamatyala e-COVID-19 lukhokelele kwimfuno enkulu kubo.Ukuba awukwazi ukuzifumana kwi-intanethi, nceda ufowunele ikhemesti yendawo yakho (ezi mvavanyo zihlala zifumaneka kwidesika engaphambili).
I-Abbott BinaxNgoku i-COVID-19 i-antigen yokuzivavanya ubuntununtunu: 84.6% (PDF) (ngaphakathi kweentsuku ezisi-7 emva kokuqala kweempawu) Ukuchaneka: 98.5% (PDF) (kwiintsuku ezisi-7 emva kokuqala kweempawu) Uvavanyo lubandakanya: iindleko ezimbini: $24 Ubukho: Amazon, CVS, Walmart
Uvavanyo lwe-Ellume COVID-19 lwasekhaya (isicelo siyafuneka) Uvakalelo: 95% (PDF) Ubucacileyo: 97% (PDF) Uvavanyo lubandakanya: 1 Iindleko: $35 Ukufumaneka: Amazon, CVS, Target
Uvakalelo loVavanyo lweQuidel QuickVue kwi-COVID-19: 84.8% (PDF) Ukucaciswa: 99.1% (PDF) Uvavanyo lubandakanya: iindleko ezimbini: $25 Ubukho: Amazon, Walmart
Isitshixo ekufumaneni iziphumo zovavanyo lwe-antigen oluthembekileyo luvavanyo rhoqo.“Uvavanyo oluqhubekayo lunokonyusa ubuntununtunu,” utshilo uChristoper Brooke, ingcali yezifo ezosulelayo kwiDyunivesithi yase-Illinois e-Urbana-Champaign."Amathuba ovavanyo olubi kabini emva kokuba wosulelekile asezantsi kakhulu kumathuba ovavanyo olunye olungenayo."
Iimvavanyo ze-antigen zasekhaya ze-Abbott, i-Ellume kunye ne-Quidel ayifuni ukuba i-swab ityhilwe kwi-nasopharyngeal cavity, onokudibana nayo kwindawo yovavanyo lwekliniki, kodwa ifuna i-swab ye-nasopharyngeal engena ngaphantsi.Uvavanyo ngalunye lunemiyalelo ethile kwaye ngokusisiseko lufuna ukuba usule impumlo yakho, udibanise i-swab kwisisombululo, udlulisele esinye isisombululo kwisitya esincinci, kwaye ulinde umphumo.
Emva kwemizuzu eyi-15, unokufunda iziphumo ze-Abbott BinaxNow kunye ne-Quidel QuickVue yovavanyo, njengokufunda uvavanyo lokukhulelwa ekhaya: imigca emibini ibonisa iziphumo ezilungileyo kunye nomqolo omnye (ulawulo) ubonisa iziphumo ezibi.Umgca wesibini otyhafileyo kakhulu usengabonisa isiphumo esihle.Uvavanyo lwasekhaya lwe-Ellume COVID-19 lufuna uqhagamshelo lweBluetooth kwifowuni ephathwayo ukunika iziphumo kwimizuzu eli-15 nge-app eyiqabane (iOS, Android).Ngokomgaqo-nkqubo wabucala wenkampani, i-Ellume kufuneka inike abasemagunyeni kwezempilo ngomhla wokuzalwa walowo uyisebenzisayo kunye nemeko yakhe yokuhlala kunye nekhowudi yeposi, iziphumo zovavanyo, umhla weziphumo zovavanyo, kunye nolunye ulwazi olufunwa ngumthetho.
Njengakuko konke ukuxilongwa kwe-COVID-19 (kubandakanya uvavanyo lwe-PCR), ixesha lokuqokelela iisampulu zokugqibela ezaziwayo okanye ezikrokrelekayo ukuba sesichengeni kunye/okanye ukuqala kweempawu yeyona nto inkulu echaphazela ukuchaneka kweziphumo zovavanyo lwe-antigen yasekhaya.Ngokomzekelo, kungenxa yoko le nto i-Abbott's BinaxNOW kunye neQuidel's QuickVue test suites ziza neemvavanyo ezimbini ezenzelwe ukusetyenziswa iintsuku ezimbini ukuya kwezintathu ngaphandle.
"Ubuntununtunu bovavanyo ngokwenene buxhomekeke ekubeni uyisebenzisa nini," utshilo uDaniel Larremore, unjingalwazi oncedisayo kwisayensi yekhompyuter kwiYunivesithi yaseColorado eBoulder, osebenzise iimvavanyo zemolekyuli kunye ne-antigen ukulinganisa iziphumo zovavanyo oluphindaphindiweyo kubantu abangenazimpawu.Umthamo wentsholongwane egazini womntu owosulelweyo uyatshintsha ngokuhamba kwexesha."Xa ufikelela kumthamo wentsholongwane egazini, ukuxinana kwe-antigen kuya kuba phezulu ngokwaneleyo ukuze kuhlolwe."Ukuzivavanya kusuku emva kokuzimasa itheko nomntu obengazi ukuba une-COVID-19 ngelo xesha akunakufane kube luncedo.“Akukho luvavanyo luya kuba lunethemba kwiiyure ezingama-24 emva kokuba sesichengeni,” utshilo uLarremore.Ukuba ulinda ixesha elide kakhulu kuvavanyo, unokuphoswa yincopho yoxinaniso lwe-antigen, okuthetha ukuba ukuba uvavanyo lubhaqa i-antigen ye-SARS-CoV-2 kwisampulu yakho, kuya kufuneka ubone umgca omnyama omnyama.
"Sihlala sicebisa uvavanyo lweentsuku ezintathu ukuya kwezintlanu emva kokuba sesichengeni," utshilo uMcCarthy weYunivesithi yaseWeill Cornell.Ukuba uneempawu ezifana ne-COVID-19, akukho mfuneko yokuba ulinde uvavanyo.
Ukuba awuqinisekanga okanye ubhidekile malunga neziphumo zovavanyo lwe-antigen ye-COVID-19, nceda udibane nogqirha wakho.Ukuba kufuneka ufune uvavanyo oluqinisekisayo lwemolekyuli kuxhomekeke kwimeko yakho.U-Larremore uthe abantu kufuneka baphathe iziphumo zovavanyo oluqinisekileyo lwe-antigen njengeyona nyani, ngakumbi ukuba ezinye izinto (ezifana nokuba sesichengeni okanye ukubonakala kweempawu) zixhasa iziphumo.Oku kuthetha ukuvalelwa, ukulumkisa nabaphi na abafowunelwa, kunye nokufuna iimvavanyo zaselabhoratri zokuqinisekisa iziphumo.Funa unyango lweempawu njengoko kufuneka.NgokukaMcCarthy wase-Weill Cornell, ukuba umntu unenqanaba eliphantsi lokurhanelwa nge-COVID-19 (umzekelo, akanazimpawu, zigonyiwe, kwaye/okanye akazityhilekanga).
Ukufumana uvavanyo lwe-PCR olwenziwa ilabhoratri yeyona ndlela ilungileyo yokufumanisa ngokuchanekileyo i-COVID-19, kodwa idinga linokuba nzima ukulifumana, kwaye ngamanye amaxesha "kuthatha ixesha elide ukufumana iziphumo, kodwa iziphumo azinamsebenzi," utshilo uBrooke. kwiYunivesithi yaseMelika.Illinois.Ngokufanelekileyo, wonke umntu uya kwenza uvavanyo lwe-PCR rhoqo kwaye axele iziphumo ngokukhawuleza, kodwa oku akunakwenzeka.Uvavanyo lwe-Antigen lukholisa ukuba lolona khetho lusebenzayo ngokwenene, ngoko ke banokudlala indima ekwandiseni ukuphindaphindwa kunye nobubanzi bovavanyo kubo bonke abantu.Indima ebaluleke kakhulu. "
Eyona maski “yeyona” ilaphu yeyona ubuya kuyinxiba (hayi ingxabano).Nantsi indlela yokufumana imaski elingana, izihluzi kakuhle kwaye ikhululekile.
Esona sigqubuthelo semaski sabantwana seso baya kusinxiba kwaye bahlale besinxibile.Sincoma iimveliso ezintandathu ezikhululekile, eziphefumulayo kwaye zilungele yonke iminyaka.
Imaski ekhululekileyo inokubangela ukugquma kweeglasi.Ukuba awufuni ukuncamathela umphezulu wemaski ebusweni bakho, ukuthontsiza okuchasene nenkungu kunokunceda.(Ngoko unako isepha okanye amathe.)


Ixesha lokuposa: Sep-17-2021